“What Your Doctor May Not Tell You About Migraines” By Alexander Mauskop, M.D. and Barry Fox, PhD 

Dr. Mauskop is one of the nation’s leading authorities on migraines. He is director of the renowned New York Headache Center, an associate professor of Clinical Neurology at State University of New York, and an attending neurologist at the prestigious Beth Israel Hospital.  In his book, Dr. Mauskop writes:

“Magnesium, Riboflavin (Vitamin B2), and Feverfew have worked wonders for many of my patients.  You can purchase the three members of this Triple Therapy individually, or combined together in a tablet called MigreLief (one tablet twice a day).  I’ve had a great deal of experience with this product, having studied it at my clinic and given it to many of my patients… MigreLief is highly effective, convenient, and reasonably priced!”

Find more information about MigreLief on our product page.

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Rebound Headaches – Why Your Migraine Medicine May Be Working Against You

Many chronic migraine sufferers resort to taking prescription medicines named triptans when a migraine gets out of control. These medicines are used “acutely”. This means you take them when you already have a migraine you want to stop. These drugs do not prevent migraines from occurring.

In fact, not only do they not prevent migraines, the general consensus amongst researchers and clinicians is that on-going regular use of triptan drugs like Imitrex or Zomig actually increase the total number of migraines that many users of the drugs have. This phenomenon is known as “Rebound Headache.”

Some readers of this article may recognize this pattern in their own lives. A migraine develops that won’t go away and one of these drugs is administered. The current migraine either goes away or decreases in intensity to the point where it is manageable but a day or two later, another migraine occurs. “The Rebound Headache”.

If users are not careful this can lead to increasing drug use and a cycle of reoccurring migraines. This rebound cycle occurs not only with triptan drugs but with caffeine containing over the counter medicines like Excedrin. Caffeine can help reduce the pain of headaches and migraines in some sufferers. But unfortunately it is caffeine that causes many headaches and contributes to the development of migraines in many, if not most sufferers. In fact, several well known neurologists who specialize in treating migraine sufferers have stated that one of the most powerful ways to reduce the number of migraines that sufferers experience is to remove caffeine from their diets. Unfortunately, this is easier said than done, because caffeine is addictive and many sufferers when attempting to ween off of it actually go through withdrawal like symptoms and experience a temporary, short increase in their headaches or migraines. Fortunately, this will last only a short time, perhaps several days and then a significant decrease in the frequency and intensity of migraines should occur.

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Riboflavin (Vitamin B-2) – Helpful in the natural treatment of migraine headaches

Another helpful and natural product for the treatment of migraine headaches is Riboflavin (Vitamin B-2) which is a precursor of flavin adenine dinucleotide (FAD).   Migraine sufferers normally suffer mitochondrial energy deficiencies, which Riboflavin (Vitamin B2) can improve when given in high dosages.  This coenzyme is an important component of the electron-transport chain.  A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone.  This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain.

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Magnesium is another natural substance that is recommended for the control and treatment of migraine headaches.

Magnesium is a nutritional supplement with numerous effects that support cerebrovascular tone.

These include:

1) inhibition of platelet aggregation
2) interference with synthesis, release, and action of inflammatory mediators
3) direct alterations of cerebrovascular tone
4) inhibition of vasospasm
5) stabilization of cell membranes

Some migraine sufferers with poor cerebrovascular tone have been found to have low brain levels of magnesium. Recommended daily dosages of Magnesium typically range from 200 to 600 mg to compensate for this deficiency — far above what’s found in most multi-vitamins.

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Puracol Feverfew is a superior form of feverfew shown to be effective with the control and prevention of migraine headaches.

Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum parthenium) is rich in compounds known as sesquiterpene lactones. One of the more important of these compounds may be parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew. Some scientific studies indicate that while parthenolide may be important there may very well be other phytochemicals in feverfew that are as of yet unidentified and play a role in its effectiveness. Some studies of extracts of feverfew containing parthenolide yielded no significant benefits. This led researchers to believe that certain of the unidentified phytochemicals may have been left behind during the extraction process. The ideal solution would be a non-extracted feverfew product that naturally contained high levels of parthenolide and kept all of the other naturally occurring phytochemicals as well.  Thus Puracol Feverfew, a non-extracted plant source with high levels of naturally occurring parthenolide was developed. Puracol Feverfew is superior in it’s effectiveness as it delivers optimal dosages of parthenolide.  Scientific studies have found parthenolide inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules.  It has also been shown to inhibit pro-inflammatory prostaglandin synthesis and the release of arachadonic acid. Each of these phenomena are associated with migraines.  European studies have shown the benefits of feverfew on long-term cerebrovasular tone.

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